ABEC expands process sciences support for biomanufacturing

Key Takeaways

• ABEC expands its Process Sciences group to support biopharmaceutical manufacturers
• The Process Sciences team combines chemical and bioengineering expertise with advanced modeling and custom equipment design
• ABEC's approach focuses on deep process understanding, analyzing critical parameters to optimize bioprocesses
• The company's dedicated facilities support process validation through real-world mixing studies and simulations
• ABEC uses Computational Fluid Dynamics (CFD) to reduce development time and cost

Introduction to ABEC's Process Sciences Expansion

ABEC, a leading provider of biomanufacturing solutions, has announced the expansion of its Process Sciences group. This move aims to help biopharmaceutical manufacturers accelerate development, reduce risk, and improve productivity across the bioprocess lifecycle. By integrating chemical and bioengineering expertise with advanced modeling, experimental testing, and custom equipment design, ABEC's Process Sciences team provides comprehensive support to customers from early development through commercial production.

Process Sciences Approach

At the core of ABEC's Process Sciences approach is a deep understanding of bioprocesses. Engineers analyze and optimize critical parameters, including:

• Mass transfer: 0.1-10 kg/m³
• Agitation: 100-10,000 rpm
• Blend time: 1-100 minutes
• Shear: 0.1-100 N/m²
• CO₂ stripping: 0.1-10 mmol/L
  to meet specific process objectives and avoid common mixing and scale-up challenges. This expertise spans both microbial fermentation and animal cell culture processes, allowing ABEC to deliver tailored solutions across a broad range of biomanufacturing applications.

Comparison of Biomanufacturing Approaches

Facilities and Simulations

ABEC's dedicated facilities support process validation through real-world mixing studies and live cell or microbial runs at scales from 200mL to 6,000 liters. These activities are complemented by CFD and other modeling tools, providing data to support Quality by Design initiatives and process characterization. Advanced CFD simulations help reduce development time and cost by minimizing experimental runs and de-risking scale-up and technology transfer decisions.

Bottom Line

ABEC's expansion of its Process Sciences group is a significant step forward in supporting biopharmaceutical manufacturers. By combining deep process understanding, advanced modeling, and custom equipment design, ABEC enables faster troubleshooting, more efficient scale-up, and reliable technology transfer while maintaining product quality and consistency. With its dedicated facilities and CFD simulations, ABEC is well-positioned to help biomanufacturers accelerate development and improve productivity.